Shorten Individuals With Explained for Students (Easy Guide)

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Shorten “Individuals with CD may have no specific symptoms other than an “irritable bowel” for several years. Symptoms vary according to the location of the disease but are similar to those for UC. Diarrhea is one of the most common symptoms and, occasionally, rectal bleeding if the colon is involved. Other manifestations are related to the location and extent of intestinal involvement. Inflammation of the ileum, for example, causes tenderness in the lower right side of the abdomen, and the individual may be anemic as a result of malabsorption of vitamin B12 . There also may be deficiencies in folic acid, vitamin D absorption, and calcium leading to bone disease. Proteins may be lost, leading to hypoalbuminemia. Weight loss is common. Anal manifestations occur in about 30% of cases, including anal fissure, perianal abscess, and fistula. Individuals with CD of long duration also are at risk for intestinal adenocarcinoma. Extraintestinal manifestations include arthropathies, skin, oral, and ocular lesions and may be the presenting symptoms.

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