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Respond and provide further suggestions on how their database search might be improved. reference within five years in APA Clinical Issue of Interest and Database Search Strategies I have selected pain management in patients with sickle cell disease (SCD), particularly during acute pain crises, as my clinical emphasis for this course. Frequent episodes of severe pain are prevalent among SCD patients, diminishing their quality of life and elevating hospitalization rates (Kavanagh et al., 2022). Provider prejudice, limited access to care, and inconsistencies in treatment protocols lead to numerous patients experiencing insufficient pain management, notwithstanding advancements in pain control (Fetta, & Evans, 2021). My study focuses on identifying medicines that enhance pain relief and patient outcomes during hospitalization. PICOT Question: In hospitalized patients with sickle cell disease experiencing acute pain crises (P), how does red blood cell transfusion (I), compared to opioid therapy alone (C), affect pain reduction and length of hospital stay (O) during the acute care period (T)? I started my inquiry by examining original sources located at the Walden University Library. I retrieved almost 300 results from several databases, including MEDLINE and CINAHL, using the keywords “sickle cell disease” and “pain management.” The results were narrowed to around 80 articles with the inclusion of the Boolean operator AND “acute pain crisis.” The search was further refined by include “opioids” and “red blood cell transfusion,” resulting in a reduction of hits to 18. The count of pertinent papers was diminished to 10 when we confined our selection to peer-reviewed, full-text original research published in the last five years. To enhance the thoroughness and efficiency of the search, I employed various strategies. I started by employing MeSH (Medical Subject Headings) terms such as “sickle cell anemia,” “analgesics,” and “blood transfusion” to enhance dependability (Walden University Library). Furthermore, I employed subject filters, including demographic age groups (adults versus children) and study types (systematic reviews versus clinical trials). By restricting my search to “randomized controlled trials,” I was able to discover more substantial evidence. By employing these strategies, I successfully refined my search, discarded irrelevant results, and gathered high-quality material to support evidence-based therapy for managing pain crises associated with SCD.
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