Researchers Exploring Whether Explained for Students (Easy Guide)

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Key Explanation

This topic involves researchers exploring whether. A strong answer should include explanation, application, and examples.

Original Question

Researchers are exploring whether race is associated with an increased risk of neuroleptic-associated dystonic reactions. Participants will include new admissions to acute psychiatric hospitals who are prescribed haloperidol, risperidone, or olanzapine. In addition to recording demographic variables (e.g., age, sex, race), pharmacogenomic testing will be obtained to measure metabolizer status at cytochrome P450 2D6. During the analysis, significant associations were found between dystonic reactions and the use of both haloperidol and risperidone in the White population as compared to other races. Which of the following would be the best step in further analysis? Expanding the study to include psychiatric outpatients Randomly assigning patients to the medications being assessed Removing olanzapine from the analysis since the dystonic risk is known to be rare Testing the association while controlling for metabolizer status at cytochrome P450 2D6

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