Rephrase Objective This Question & Answer Guide (With Explanation)

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Original Question

rephrase ” The objective of this study was to evaluate an intervention designed to improve medi cation safety for PWD and their carers during an unplanned admission to hospital, and this paper reports the effect of the intervention on polypharmacy, PIMs, and anticholiner gic burden. Polypharmacy was high overall (>90%) and this reflects high comorbidity in this study population, and increasing comorbidity has been reported to be significantly associated with higher polypharmacy [25]. This result is higher than the rate reported in a study of older people including participants with cognitive impairment (n = 373) with a rate of 69% for polypharmacy [25] and a study that included (n = 10,528) participants with dementia in primary care of 57% [3]. These results indicate that polypharmacy is lower in the community for PWD. Nonetheless, reduced prescribing reduces medication-related risk for PWD [1,25,26]. PIMs prescribing was very high (>90%) overall in this study. PWD who suffer esca lated BPSD during a hospital admission may be temporarily managed with PIMs such as psychotropics, sedatives, or hypnotics. Previous studies have reported lower rates of PIMs prescribing (of at least one PIM) for PWD in the community. A multi-country study (n = 2004) reported a rate of 60% [4] and a nationwide study in New Zealand (n = 2190) reported a rate of 67% [27]. However, a recent systematic review reported that prevalence of PIMS ranged from 53-90% for inpatients with cognitiv

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