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please help with these multiple-choice questions n the pathophysiology of Alzheimer’s Disease, there are certain proteins that lead to the plaques and tangles that result in this progressive, irreversible brain disorder. Choose the appropriate protein with its corresponding pathology. I. Tau – tangles II. Beta-amyloid – tangles III. Tau – plaques IV. Beta-amyloid – plaque When can buprenorphine be initiated in a patient who is suffering from an opioid overdose? A . As soon as the patient is stabilized B . It should be administered as soon as you find the patient unconscious C . Right after naloxone is administered to prevent the patient from going back into opioid overdose D . When the patient is experiencing mild-to-moderate symptoms of withdrawal Choose the correct statement regarding an anti-ADHD medication and its respectful mechanism of action A . Methylphenidate – blocks reuptake of dopamine in the pre-synaptic neuron and promotes release of dopamine from their storage sites in the pre-synaptic neuron B . Amphetamines – blocks reuptake of norepinephrine and dopamine into presynaptic neurons C . Clonidine – blocks reuptake of dopamine in the pre-synaptic neuron and promotes release of dopamine from their storage sites in the pre-synaptic neuron D . Atomoxetine – acts by blocking the norepinephrine pump on the pre-synaptic membrane E . Guanfacine – blocks reuptake of norepinephrine and dopamine into presynaptic neurons. Select the correct description of a somatoform disorder. A . Somatization disorder – manifests as a pain syndrome with a significant loss of or alteration in physical function that mimics a physical disorder B . Conversion disorder – pain that causes significant impairment in occupation or social function, induces marked distress, or both C . Hypochondriasis – persistent belief that one has a serious illness, despite extensive medical evaluation D . Pain disorder – intentional production or feigning of physical symptoms Which features are consistent with delirium? I. Acute onset II. Gradual onset III. Course of disease fluctuates IV. Course of diseases does not fluctuate V. Impaired attention VI. Normal attention A . II, IV, and VI B . I and III C . II and IV D . I, III, and V Patient is a 10-year-old female with diagnosed ADHD who was started on Ritalin 5 mg twice a day over 2 months ago. She is still experiencing the triad of symptoms associated with ADHD (impaired attention, impulsivity, and excessive motor activity). Her mother reports that she is now having difficulty in falling asleep since starting the medication. She has been on no other anti-ADHD medications and the mother reports full compliance with medication regimen. What is the appropriate recommendation to make based on this scenario? A . Recommend psychotherapy in addition to current treatment B . Switch to low dose Focalin C . Add Clonidine D Switch to low-dose Adderall and titrate as appropriate in addition to . psychotherapy Which medication(s) requires a test dose to determine accurate use of the drug (i.e., how addicted the patient truly is on a certain drug) before beginning a titration schedule to withdraw the patient? I. Butalbital II. Lorazepam III. Hydrocodone A . I only B . II only C . III only D . I and II Drug addiction includes many prescription medications and illegal substances. Of the drugs listed, which ones can be withdrawn abruptly WITHOUT medical intervention to prevent withdrawal seizures? A . Alcohol B . Adderall C . Lorazepam D . Butalbital. Select the correct treatment regarding drugs involved in addiction management and their corresponding mechanism of action. A . Benzodiazepines – GABA antagonist B . Buprenorphine – opioid antagonist C . Naltrexone – partial opiate agonist D . Flumazenil – GABA antagonist

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