Medication Salbutamol Mechanism Question & Answer Guide (With Explanation)
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This question relates to medication salbutamol mechanism and requires a structured academic response.
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Original Question
Medication: Salbutamol Mechanism of Action: Salbutamol is a short-acting β2-adrenergic receptor agonist (SABA). It works by binding to β2 receptors in the smooth muscle of the airways, leading to activation of adenylate cyclase and an increase in cyclic AMP (cAMP). The rise in cAMP activates protein kinase A, which in turn inhibits phosphorylation of myosin, decreasing intracellular calcium levels and causing relaxation of bronchial smooth muscles. This results in bronchodilation, thereby relieving acute bronchospasm and reducing airway resistance to improve airflow. Rationale for Prescription: Salbutamol is prescribed to Mick to manage acute exacerbations of breathlessness in COPD by temporarily relieving bronchospasms. It is a common rescue medication for fast relief of symptoms such as wheezing and dyspnea, which can be critical in preventing more severe respiratory distress.
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