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Medical Examiner Office Assignment Help: How to Answer This Question

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What This Question Is About

This question relates to medical examiner office and requires a structured academic response.

How to Approach This Question

Structure your response with introduction, analysis, and conclusion.

Key Explanation

This topic involves medical examiner office. A strong answer should include explanation, application, and examples.

Original Question

The Medical Examiner’s office calls to inform you that they are investigating the sudden death of one of your patients. The patient in question was Linda Guinness, a 55-year-old black woman who had been followed for many years in the hypertension clinic. Work-up at various times had revealed no evidence of renal disease or endocrine abnormalities. On a recent office visit, her BP was measured as 190/105 mm Hg. A few months ago, she was briefly admitted to a hospital after she awakened at night feeling short of breath. Review of hospital records from that admission shows that she had mild ankle edema, basilar rales, and hepatomegaly on initial evaluation. A chest x-ray showed cardiomegaly and slight atrial enlargement. An ECG confirmed left ventricular hypertrophy. Laboratory studies at that time suggested slight hepatic damage; serial cardiac serum markers (enzymes, troponin) were negative for myocardial infarction. Over the last few years, there had been a steady increase in her serum BUN and creatinine. The medical examiner relates that the patient complained of sudden, severe, sharp chest pain and collapsed at her husband’s softball game. She was taken to a hospital, where she was noted to be hypotensive with unequal pulses. A chest x-ray revealed a left pleural effusion and a widened mediastinum. An autopsy is being done to determine whether she died from some catastrophic vascular event related to her hypertension. In which inherited disease is aortic dissection a serious complication?

 
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