Mark Male With Assignment Help: How to Answer This Question

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Original Question

Mark is a 48 yo male with a past medical history of rheumatoid arthritis and hypertension who presents to the pain clinic for evaluation. He reports chronic refractory pain due to an L5 and S1 intervertebral disc herniation for which he underwent a laminectomy. He reports failed therapies of pain relief with gabapentin, pregabalin, opioids and physical therapy prior to surgery. He has been cleared and wants to return to work. However, due to his unrelenting pain, even after surgery, he has been unable to do so. He wants to discuss if a trial of medicinal cannabis can be considered to manage his chronic pain. Alert, well-nourished, cooperative patient. Vital signs (VS) are stable with a pain score of 10/10. Rheumatoid arthritis changes noted to hands. Well healed lumbosacral scar. CSMD report confirms previous use of above controlled substances and UDS is negative for illicit drugs. 1. Which cannabinoid receptor type is found in the brain and spinal cord and is involved in pain modulation? 2. What are common potential side effects of this pharmacological agent?

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