Make This Simple Question & Answer Guide (With Explanation)
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Structure your response with introduction, analysis, and conclusion.
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Original Question
make this simple “Infants born with the classic presentation of CAH will require lifelong treatment. Early diagnosis through newborn metabolic screening is key, as is follow-up of any signs of atypical genitalia” (Allis, 2021).). In the case of newborn baby girl, follow up was missed after presentation of atypical genitalia, and she is now experiencing the detrimental effects of this with symptoms portraying progression to adrenal crisis. “The initial goals of treatment are to establish physiologic levels of cortisol and aldosterone and avert an adrenal crisis. Correction of these levels will also suppress the overproduction of androgens by reducing ACTH stimulation” (Allis,2021). The American Academy of Pediatrics supports the clinical guidelines for treatment provided by The Endocrine Society. Recommended therapy is hydrocortisone for glucocorticoid replacement and fludrocortisone as the mineralocorticoid replacement, and these infants will typically need sodium replacement, as the standard sodium amounts provided by human milk and infant formulas are not sufficient to meet their physiologic demand (Allis, 2021). Proper treatment and robust follow-up care with a pediatric endocrinologist will ensure prevention of adrenal crisis. “While maintenance therapy is important, so is the need for stress dosing of cortisol replacement for CAH patients during episodes of illness” (Allis, 2021). Therefore, during periods of acute illness such as respiratory infection, febrile illness,
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