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EXPAND- The Nordic registry-based study, authored by Magnus et al. (2024), aimed to evaluate the risk of major congenital anomalies in infants born to mothers who had a COVID-19 infection or vaccination during the first trimester of pregnancy. Utilizing data from 343,066 live-born singleton infants in Sweden, Denmark, and Norway, the researchers categorized anomalies using the EUROCAT system. Adjusted logistic regression analyses accounted for confounders such as maternal age, parity, and chronic conditions. The results indicated no increased risk of congenital anomalies associated with COVID-19 infection or vaccination, supporting the safety of COVID-19 vaccination during pregnancy.

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