Case Study Came Assignment Help: How to Answer This Question
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Original Question
Case Study 1:JB came in for genetic counseling at age 40 due to her concern about her mother’s history of breast cancer at age 44 and her wish to be proactive in surveillance and prevention measures. Her mother’s only sister died at age 60, and her maternal grandmother died at age 86; neither of them had been diagnosed with cancer of any kind. There was also a history of colon cancer in JB’s father at age 52.According to guidelines from the National Comprehensive Cancer Network (NCCN), JB meets the criteria for testing for hereditary breast and ovarian cancer. Question 1:What is that criterion (that JB meets)? Question 2:Who should be tested for BRAC 1 and BRAC 2 (the prob and from the ones above)? Case Study 1 – Part 2:In JB’s case the genetic screening revealed a mutation in the BRCA 2 gene (results from proband testing, not JB) Question 3:What treatment and follow-up do you recommend in the person who was genetically tested and who was positive for the BRAC2 gene (for proband tested above)? Case Study 1 Part 3: You refer JB for genetic counseling, and the genetic testing and the mutation found in her family is tested. The result shows that JB is negative for that genetic mutation. (JB negative but proband was positive). Question 4:What do you advise JB regarding her risk for breast and ovarian cancer? Question 5:Because her father also has a history of colon cancer, what do you recommend for her for screening for colon cancer?
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