Break This Down Assignment Help: How to Answer This Question

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Structure your response with introduction, analysis, and conclusion.

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Original Question

break this down into simple words: The results from the meta-analysis show that PQNP doubled the odds of quitting successfully over and above the current regimen for nicotine patches, which involve starting patch at the quit date. The results were observed not only in short-term outcome (6 weeks), but also held up in longer-term outcome (6 months). Across the varied studies analyzed here, PQNP appears to produce a robust and replicable increase in cessation rates compared to current patch regimens. The four studies included in this meta-analysis used substantively different study conditions during the pre- cessation treatment period. One of the four studies ran- domized subjects to mecamylamine treatment prior to cessation [4], two studies varied the nicotine delivery of cigarettes smoked during pre-cessation treatment [5,6] and one study had subjects start pre-cessation treatment 4 weeks prior to quitting [4], rather than 2 weeks, as in the other studies. Finally, one of the studies used a 15-mg, 16-hour patch [7], while the others used either 21-mg 24-hour Habitrol [4,5] or NicoDerm [6] patches (which have themselves been shown to differ in terms of nicotine delivery [13]). The four studies also differed in the treat- ment subjects received post-cessation and in the timing of abstinence evaluation. Some studies had also tested mecamylamine treatment; however, the pooled effect size for PQNP was similar whether or not mecamylamine was used. It seems clear that mecamylamine a

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