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based on this. what is the indication of Timolo? Five β blockers—betaxolol, carteolol, levobunolol, metipranolol, and timolol—are approved for use in glaucoma. Dosing is topical. These agents cause minimal disturbance of vision and are considered first-line drugs for glaucoma, although prostaglandin analogs are becoming favored. The β-adrenergic blockers lower IOP by decreasing production of aqueous humor. Reductions in IOP occur with “nonselective” β blockers (drugs that block β1 and β2 receptors) as well as with “cardioselective” β blockers (drugs that block β1 receptors only). β blockers are used primarily for open-angle glaucoma. They are suitable for initial therapy as well as maintenance therapy. β blockers in combination with other drugs are also employed for emergency management of acute angle-closure glaucoma.

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