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Abstract: The authors investigated the role of self-reported life satisfaction in predicting mortality with a prospective cohort study (1976-1995). A nationwide sample of healthy adults (18-64 years) responded to a questionnaire about life satisfaction in 1975. A summary score for life satisfaction (LS), defined as interest in life, happiness, loneliness, and general ease of living (scale range 4-20), was determined and used as a three-category variable: the satisfied (LS, 4-6) (21%), the intermediate group (LS, 7-11) (65%), and the dissatisfied (LS, 12-20) (14%). Mortality data were analyzed with Cox . Dissatisfaction was linearly associated with increased mortality. The age-adjusted hazard ratio of all-cause, disease or injury mortality among dissatisfied men versus satisfied men were 2.11 (95% CI, 1.68-2.64), 1.93 (95% CI, 1.40-2.39) and 3.01 (95% CI, 1.94-4.69), respectively. The authors conclude that life dissatisfaction may predict mortality and serve as a general health risk indicator. Methods: Baseline questionnaire sent by mail in 1975. 31,133 subjects responded. Eligibility for this study: deemed by self-reporting on a questionnaire as being healthy at baseline. (a) If the entity of life satisfaction was measured with perfect accuracy and reproducibility and then dichotomized into “satisfied” and “dissatisfied” (with the intermediate group discarded), and assuming no losses to follow-up, the following sample of data would result at the end of 1995. Consider this the truth for this study population: Exposure Outcome Life satisfaction Death No Death (Exposed) Dissatisfied 67 1673 (Unexposed) Satisfied 187 9412 Calculate the preferred measure of association between life dissatisfaction and mortality that can be calculated using these data, and explain your choice. (2 pts)
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