Get Answer: Question Refer Formulary Question Guide

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Original Question

Question: Refer to the formulary of cetrimide cream aqueous from the Australian Pharmaceutical Formulary and Handbook (APF – 24th edition related pages available in RMIT library) and answer the following questions: A. Identify the function of each component in the cream? B. Discuss the possible instability of the cream if it was mixed with the following drugs. Your answer should include the mechanism of the instability (if it occurs) in each case. Neomycin (as Neomycin sulfate) Chlorhexidine (anion) C. Discuss the difference between “flocculation” and “coalescence” in the context of pharmaceutical emulsions and creams. Your answer should include causes. D. Discuss the importance of thixotropy for cetrimide cream. Your answer should include the description of this rheological flow behaviour and how this can be identified using a viscometer.

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