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Make a FLOWCHART for this pathophysiology. Pathophysiology of Compartment Syndrome In compartment syndrome, there are 3 parts of the body involve, the muscle, the nerves and the blood vessels, which is surrounded by fascia (tissue that surrounds the muscle to keep then intact during contraction and also helps to attach the muscle to the bone), and when an accident or trauma happen, this can lead to increase pressure (this is because the fascia that surrounds the compartments is not elastic, so when it is compressed due to trauma, it stays it the way), which can impede the blood flow, and results which hypoxia in the area. To understand clearer, when an accident or trauma in the right leg happen, like in this case, structures inside the right leg were compressed, and the veins and arteries are the first one that are greatly affected, which cause low oxygenation (hypoxia), which leads to the release of different substances such as histamine and nitrous oxide, This event can affect the blood vessels permeability which causes the water to leak out, resulting to extracellular edema, which can add more pressure in the compartments. Also, low oxygenation (hypoxia) can affect the muscle cells, it can disturb the sodium potassium pump, which cause inability to move out the sodium, which leads to movement of water inside the cell, resulting to intracellular edema, and more pressure will happen. So all of these events will results to the signs and symptoms which are commonly called the 6 P’s (pain, paresthesia, pallor, paralysis, poikilothermia, and pulselessness). In this case, the patient is experiencing increase pain intensity, this is due to the compression of nerves within the compartment and numbness (paresthesia), and this is because of low blood supply, it cuts off nerve function, and can cause nerve damage. Also, movement of water to extracellular and intercellular area from the blood vessel can lead to low blood volume which causes hypotension. Increase in heart rate and respiratory rate are due to the pain and stress response of the body.

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