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Hi Professor, can you briefly discuss the specific therapy for any of the patients presented Finally, the medications react with patient according to their body, so everyone will not get the same side effects and it may vary. So what is different in older patients what would be the “best choice” in this population and why? Benzodiazepines are commonly prescribed medications for several indications, including anxiety and sleep disorders. Safety: How could the side effect profile affect your patients? Efficacy: Are benzodiazepines efficacious for anxiety and sleep? Use: Are they under or over prescribed? How can we ensure safe use of these medications? Consider the following cases: KT is a 24 year old female completing her studies. While home for spring break, she presents to her primary care physician because she has been worried about her academic, professional, and personal future since class restarted in late August. She is constantly worried about passing all of her exams and that she is going to be the only one of her friends that graduates school without a ring on her finger. How would you help her assuming she meets the criteria for GAD? WD is a 49-year-old male who suffered a myocardial infarction one week ago. Upon discharge, it was noted that WD appeared depressed. At a follow-up visit with his physician a week later, WD met criteria for a diagnosis of major depressive disorder. His past medical history includes: treatment refractory hypertension, diabetes mellitus (type II), and severe uncontrolled narrow angle glaucoma How would you help him assuming he meets the criteria for MDD? JM is a 42 year old female who was referred for management of insomnia. She reports that she is unable to sleep at all during the week (difficulty going to sleep and staying asleep) and sleeps all day on Sunday. She currently takes temazepam (Restoril) 30 mg HS (recently increased from 15mg). She also experiences depression due to an abusive relationship with her boyfriend as well as her current lack of employment. She reports poor sleep hygiene (reads and watches TV in bed), drinks 6-8 cups of coffee throughout the day and does not pay attention to how late she eats or exercises. What non-pharmacological and pharmacological therapies would you recommend for JM?

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