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Original Question

Question 2 [10 marks] Test A is a gold standard method to determine disease ‘X’. Two other new test methods, B and C were compared with Test A. A method evaluation was done using Bland-Altman plots. The graphs are shown below. Analyse the charts plotted and conclude if the new tests (Test B and C) are suitable to replace the gold standard (Test A). Provide relevant justifications for your conclusion. [6 marks] It is reported that Test A has a sensitivity of 98% and specificity of 75%. Is Test A more suitable to be used as a screening test or as a confirmatory test? Justify your answer. [4 marks] Image transcription text 40.72 #1.96SD Difference between A and B Mean -1.965D -4.89 9 655 56.64 Mean of A and B Figure 1: Bland-Altman Plot showing the comparison … Show more

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