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respond to this post…. Systemic Lupus Erythematosus (SLE) is a type III hypersensitivity reaction that presents as a chronic inflammatory condition with the potential to damage a variety of cell types, though its pathogenesis is not completely understood (Nath, 2023). More common in women, SLE includes periods of exacerbation and remission. When the body loses its ability to recognize its own cells, it becomes overreactive through molecular mimicry or changing antigens to appear harmful (Siegel & Sammaritano, 2024). The body’s typical process of removing harmful cells through apoptosis is disrupted, causing antibody formation and T cell attacks on organs and tissues that can cause long-term damage (Siegel & Sammaritano, 2024). To develop SLE, a person usually needs to have both a genetic risk and exposure to environmental triggers (Nath, 2023).

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