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Reply to your peer’s below in 100-150 words include in-text citations and one reference between 2023-2025. Hypersensitivity reactions are exaggerated immune responses to allergens, ranging from mild to life-threatening. Symptoms can include localized rash, itching, nasal congestion, and gastrointestinal distress. Anaphylaxis, a severe hypersensitivity reaction, presents rapidly and may include urticaria, angioedema, respiratory distress, hypotension, dizziness, and gastrointestinal symptoms such as vomiting or diarrhea (Cardona et al., 2020). Without prompt treatment, it can lead to airway obstruction, shock, and death. Differentiating anaphylaxis from other conditions, such as asthma, panic attacks, or vasovagal syncope, requires careful assessment. Distinguishing factors include sudden onset of symptoms, involvement of multiple organ systems, and rapid progression following allergen exposure. Nurses must assess for signs such as wheezing, stridor, low blood pressure, and a known trigger like food, medication, or insect sting (Shaker et al., 2020). If anaphylaxis is suspected, immediate administration of intramuscular epinephrine is the first and most critical step. The nurse should then call for emergency support, maintain airway and oxygenation, and monitor vital signs closely. Timely recognition and intervention are essential to prevent complications that may include death. References Cardona, V., Ansotegui, I. J., Ebisawa, M., El-Gamal, Y., Fernández Rivas, M., Fineman, S., … & Beyer, K. (2020). World allergy organization anaphylaxis guidance 2020. World Allergy Organization Journal, 13(10), 100472. https://doi.org/10.1016/j.waojou.2020.100472 Shaker, M. S., Wallace, D. V., Golden, D. B. K., Oppenheimer, J., Bernstein, J. A., Campbell, R. L., … & Greenhawt, M. (2020). Anaphylaxis: A 2020 practice parameter update, systematic review, and GRADE analysis. The Journal of Allergy and Clinical Immunology, 145(4), 1082-1123. https://doi.org/10.1016/j.jaci.2020.01.017

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