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Original Question

1. Define quantitative platelet disorders. 2. Identify the types of bleeding that are seen in platelet disorders. 3. Differentiate platelet abnormalities that are due to acquired defects: drug induced, nonimmune, or vascular related. 4. State how preanalytic variables may affect the platelet count. 5. Describe three characteristics of the qualitative platelet disorders von Willebrand disease, Bernard-Soulier syndrome, and Glanzmann’s thrombasthenia. 6. Identify drugs that are implicated in immune thrombocytopenia. 7. Evaluate conditions that may cause thrombocytosis. 8. Compare and contrast acute versus chronic idiopathic thrombocytopenic purpura in regard to pathophysiology, clinical symptoms, and treatment. 9. Define hemolytic uremic syndrome in terms of pathophysiology, key clinical features, and patient management. 10. Define thrombotic thrombocytopenic purpura in terms of pathophysiology, key clinical features, and severity.

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