Small Pilot Study Assignment Help: How to Answer This Question
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Original Question
small pilot study assessed survival time in 42 leukemia patients. There were 21 females and 21 males. Also measured was the log of the white blood count (WBC) as it is a known prognostic indicator for survival in leukemia patients. The logarithm of the white blood count was used because the raw values are typically skewed. The STATA dataset (Problem 1) is available on the D2L site. The variables available are: Variable Description Codes/Values id Participant id 1 – 42 time Time to death (weeks) 1 – 35 died Death 0 = No 1 = Yes sex Sex 0 = Female 1 = Male log_WBC Logarithm of the WBC 1.45 – 5.00 a) (5 points) Plot the Kaplan-Meier estimate of the survival time for females versus males. b) (5 points) What is the median survival time for females versus males? c) (5 points) Is there a statistically significant crude association between survival time and sex? What is the appropriate hazards ratio and p-value? Interpret this hazards ratio in terms of the difference between females and males. d) (5 points) A scientific concern is that the log of the WBC may have a different impact on survival for females versus males.
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