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Question for Reading Assignment Please note: a few of these questions may require you to research outside of the WHO Bulletin 1. According to the WHO, what is the only thing that outperforms vaccines in preventing infectious disease? 2 . True or False, vaccines that prevent disease have been shown to be safer than the therapeutic medicines which treat disease. 3. According to the WHO, which diseases had recently increased prior to the publication of this bulletin due to misguided antivaccination campaigns? 4. True or False, negative aspects of vaccines get much more attention and press than positive aspects of vaccines. 5 . What disease has been eradicated from the planet by the use of vaccination? 6. Which disease is next targeted for eradication through vaccination? 7 . What is the difference between eradication and local elimination? 8 . In areas where vaccination against measles with the MMR vaccine has been at 95%, local elimination of the disease has occurred. According to the WHO what was the average MMR vaccination rate in Africa (where measles was still present) in 2004? 9. What does it mean for a disease to have an “environmental reservoir”? What about an “animal reservoir”? 10. Why do you think the WHO says it may not be possible to eradicate a disease with an environmental or animal reservoir? 11. What is an efficacious vaccine? 12. What vaccines may still be effective even when given (soon) after exposure to the disease they are meant to prevent? 13. Each year, vaccines are estimated to prevent how many deaths globally? 14. The 9 diseases for which we have had a vaccine available for decades have seen how much decrease in occurrence in the USA? 15. True or False, when a disease does occur in a person that was vaccinated for that disease, the signs and symptoms are usually much milder than they would otherwise be 16. What is “sterilizing immunity”? 17. What is “herd protection” (also sometimes called “herd immunity”)? 18. Define RO 19. True or False, diseases with a lower RO require a higher vaccination rate than those with a higher RO to provide herd immunity. 20. RO for the delta variant of COVID-19 was 5, omicron has an estimated RO of around 10, which is a VERY high RO.

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