Case Heat Stroke Assignment Help: How to Answer This Question

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Original Question

Case 1: Heat Stroke A 79-year-old woman with mild dementia and a previous cerebrovascular accident was living alone in a small, poorly ventilated apartment when a home health aide, who visited once a week, found the apartment locked during a heatwave. The health aide called the police, who forced an entrance and found the patient unresponsive in her bed. The health aide reported that the patient was taking no medications. The patient was rushed to the emergency department, where her temperature was 40.9oC. The patient was deeply comatose. Her blood pressure was not measurable; her heart rate was 160. Her skin was hot and dry; except for obesity, the physical examination was otherwise unremarkable. Her electrocardiogram revealed sinus tachycardia and diffuse ST and T-wave changes consistent with ischemia. While an intravenous line was being placed, ventricular fibrillation developed. Despite ice packs, vigorous cardiopulmonary resuscitation, and fluid replacement, she died in the emergency room. 1. Define negative feedback inhibition; describe the normal feedback loop for homeostasis; and, include definitions for the integrating center; regulated variable; controlled variable; afferent system; efferent system; and effectors. Given that the patient’s temperature was 40.9oC: 2. Explain what physiological changes take place in response to this elevated temperature. Relate this to feedback regulation. 3. Explain how these changes relate to the information that “her blood pressure was not measurable”? Relate this to feedback regulation. 4. Explain why her heart rate is 160? Relate this to feedback regulation. 5. During heat stroke, a patient massively vasodilates to dissipate heat. Explain how this vasodilation, along with dehydration due to fluid losses as a consequence of sweating, can lead to shock.

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