Once Imputed Adjusted Explained for Students (Easy Guide)
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Original Question
Once imputed and adjusted, TMG tended to a 20% cost reduction, particularly over the 2-year period (0.79 [0.61; 1.03], p = 0.0879). A significant (p = 0.06) between-group difference in glycaemic control has been previously shown, meaning that a trend for HbA1c diminution occurs in the TMG [17]. In this context, a cost-effectiveness analysis, rather than a cost-minimization analysis, is appropriate because the levels of effectiveness of the groups were not strictly equivalent. EDUC@DOM led to a €1334 cost saving and a 0.17% decrease in HbA1c over 1 year, and to a €3144 cost saving and a 0.14% decrease in HbA1c over 2 years. In the light of these results and the 95% confidence ellipses for the 1- and 2-year periods on the CEP plane, it was concluded that EDUC@DOM is a cost-effective strategy with a high probability of being a dominant strategy. We observed a significantly higher prevalence of neuropathy in the CG. Due to the relatively small sample size, the randomization may not have smoothed out all of the differences between groups. Nevertheless, only a slight impact of neuropathy on cost management was found within the multivariate analysis, with no modification of the group effect when this variable was considered. Given the limited sample size, this variable was not considered a confounding factor in the final analysis.
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