Investigator Wants Assess Assignment Help: How to Answer This Question
This type of question evaluates analytical and critical thinking skills.
What This Question Is About
This question relates to investigator wants assess and requires a structured academic response.
How to Approach This Question
Use appropriate theories and support your answer with clear reasoning.
Key Explanation
This topic involves investigator wants assess. A strong answer should include explanation, application, and examples.
Original Question
(1): An investigator wants to assess whether smoking is a risk factor for pancreatic cancer. Electronic medical records at a local hospital will be used to identify 50 patients with pancreatic cancer. One hundred patients who are similar but free of pancreatic cancer will also be selected. Each participant’s medical record will be analyzed for smoking history. Identify the type of study proposed and indicate its specific strengths and weaknesses. (2): What is the most likely source of bias in the study described in Problem 1? (3): An investigator wants to assess whether the use of a specific medication given to infants born prematurely is associated with developmental delay. Fifty infants who were given the medication and 50 comparison infants who were also born prematurely but not given the medication will be selected for the analysis. Each infant will undergo extensive testing at age 2 years for various aspects of development. Identify the type of study proposed and indicate its specific strengths and weaknesses. (4): Is bias or confounding more of an issue in the study described in Problem 3? Give an example of a potential source of bias and a potential confounding factor. (5): A study is planned to assess the effect of a new surgical intervention for gallbladder disease. One hundred patients with gallbladder disease will be randomly assigned to receive either the new surgical intervention or the standard surgical intervention. The efficacy of the new surgical intervention will be measured by the time a patient takes to return to normal activities, recorded in days. Identify the type of study proposed and indicate its specific strengths and weaknesses. (6): An investigator wants to assess the association between caffeine consumption and impaired glucose tolerance, a precursor to diabetes. A study is planned to include 70 participants. Each participant will be surveyed with regard to their daily caffeine consumption. In addition, each participant will submit a blood sample that will be used to measure his or her glucose level. Identify the type of study proposed and indicate its specific strengths and weaknesses. (7): Could the study described in Problem 6 be designed as a randomized clinical trial? If so, briefly outline the study design; if not, describe the barriers. (8): A study is planned to compare two weight-loss programs in patients who are obese. The first program is based on restricted caloric intake and the second is based on specific food combinations. The study will involve 20 participants and each participant will follow each program. The programs will be assigned in random order (i.e., some participants will first follow the restricted-calorie diet and then follow the food-combination diet, whereas others will first follow the food-combination diet and then follow the restricted-calorie diet). The number of pounds lost will be compared between diets. Identify the type of study proposed and indicate its specific strengths and weaknesses. (9): An orthopedic surgeon observes that many of his patients coming in for total knee replacement surgery played organized sports before the age of 10 years. He plans to collect more extensive data on participation in organized sports from four patients undergoing knee replacement surgery and to report the findings. Identify the type of study proposed and indicate its specific strengths and weaknesses. (10): Suggest an alternative design to address the hypothesis in Problem 9. What are the major issues in addressing this hypothesis?
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